01 · Pre-trial
Design trials that can detect change
- Imaging protocol design and imaging charter
- Power calculations and prognostic enrichment
- Site selection, training and qualification
Imaging · Machine learning · Clinical trials
Advanced data analytics for clinical trials
QSA applies the latest imaging and machine learning technologies to show more precisely where treatments are working, across every stage of a clinical trial.
Services along the trial life cycle
From protocol design to post-trial analysis
02 · During trial
Run imaging with full auditability
- Image receipt, completeness and quality control
- Visual reads by trained experts, for efficacy and safety
- Quality management (ISO 9001:2015)
03 · Post-trial
Find where treatments work
- Data-driven patient staging and subtyping
- Machine-learning prognosis
- Causal modelling and brain age
Technology and biomarkers
Trial-grade tools, from image receipt to insight
Automated image QC
Machine learning that flags image issues such as blurring, ghosting and banding.
QSlice
Processing pipelines with integrated quality control and interactive scan viewing.
QViewer
Expert review with multi-visit comparison, lesion annotation and safety reads.
QSAtrophy
Objective measurement of brain volume percentage change.
MindGlide
Deep learning for rapid brain-atrophy outcomes in phase 2 and 3 trials.
SuStaIn
Data-driven disease subtypes, with each patient staged within them.
Conventional biomarkers
- Lesion number and volume
- Whole-brain and regional volume
- Spinal cord area and change
Advanced MRI analytics
- MTR, DTI and NODDI, QSM, MTV
- Slowly expanding lesions
- Functional MRI
AI-driven stratification
- Subtyping and staging (SuStaIn)
- Prediction of treatment response
- Prognostic trial enrichment
Areas of work
Neurology and beyond
- 01
Multiple sclerosis
Subtyping, staging and advanced MRI biomarkers for MS trials.
- 02
Cell therapy
Imaging analysis for an MS trial of a cell therapy.
- 03
ARIA
An educational resource on amyloid-related imaging abnormalities.
- 04
Automated MRI quality control
Machine learning that checks scans before analysis.
- 05
Brain fingerprinting
DeepBrainPrint, a deep-learning method for brain fingerprinting.
- 06
Retinal imaging
QSA also applies its analysis methods to retinal imaging.
Evidence
Quality you can audit
- ISO 9001
- Quality management system certified to ISO 9001:2015 by BSI
- Phase 1–4
- The full range of imaging services for clinical trials
- 25+ yrs
- Of UCL imaging methods applied to clinical trial data
- 2024 · Global pharmaceutical company
A multi-year MS subtyping study through image analysis.
- 2025 · Cell therapy
A three-year imaging analysis for an MS trial of a CAR-T cell therapy.
Planning a clinical trial?
Tell us about your study and the imaging questions behind it.